PetMD Editorial
By PetMD Editorial on Nov. 7, 2012

Drug Info

  • Common Name: Apresoline®
  • Drug Type: Arterial dilator
  • Used For: High blood pressure, Congestive heart failure
  • Species: Dogs, Cats
  • Administered: 10mg, 25mg, 50mg, and 100mg tablets, Injectable
  • How Dispensed: Prescription only
  • FDA Approved: No

General Description

Hydralazine is a drug that opens up the blood vessels, treating high blood pressure and assisting in the treatment of congestive heart failure.

How It Works

Hydralazine works by relaxing the smooth muscle in the blood vessels. Nerve signals cause calcium to be released, which contracts muscles. Without calcium, muscles are unable to contract and blood vessels are unable to constrict. When Hydralazine inhibits calcium movement, the blood vessels are forced to relax, lowering the pressure inside them.

Storage Information

Read the drug label for storage information.

Missed Dose?

Give the dose as soon as possible. If it is almost time for the next dose, skip the missed dose, and continue with the regular schedule. Do not give your pet two doses at once.

Side Effects and Drug Reactions

Hydralazine may result in these side effects:

  • Hypotension
  • Vomiting
  • Diarrhea
  • Lethargy
  • Conjunctivitis
  • Water or urinary retension
  • Constipation

Hydralazine may react with these drugs:

  • Antihypertension drugs
  • Beta blockers
  • Sympathomimetic
  • Digoxin
  • Furosemide

USE CAUTION WHEN ADMINISTERING THIS DRUG TO PETS WITH KIDNEY DISEASE OR HEART DISEASE


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